DEREK HEWGILL

 3 Ivy Glen Lane

 Lawrenceville, NJ 08648

  (609) 620-0898

  martek4@juno.com

SUMMARY

Senior Research Scientist with 40 years experience in Medical Research. 30 years experience Managing, Supervising, and Operating, Flowcytometry and Imaging Facilities. Proficient in Instrument, laser, and computer maintenance, repair, modification, upgrade, and training. This has realized substantial savings in operating costs. 

Research Fields of Interest include, Drug Discovery in Immunology for Oncology, Organ Transplantation, Inflammation, Dermatology, Cardiovascular, and Metabolic Diseases.

 PROFESSIONAL EXPERIENCE

Flowcytometry Consultant and Technical Services 2002 - Present

Bristol-Myers Squibb, Princeton, New Jersey.  1997 - 2002 Senior Research Scientist Drug Discovery and Signal Transduction.

Use of Calcium Signaling, Transfection Reporters, Affinity/Avidity Assays, Optimization of Cell Lines and Reagents for High Throughput Screening, Receptor Occupancy Assays for Clinical Trials.

Oncogen/Bristol-Meyers Squibb, Seattle Washington  1986 – 1997

Supervisor, Cell Sorter Operations

Department of Immunotherapy and Cell Interactions

Standardization and molecular quantitation of monoclonal therapeutic reagents. 

Calcium analysis of stimulated cells

Cell phenotyping and cell cycle analysis

Sterile cell sorting and cloning.

Genetic Systems, Inc., Seattle, Washington.   1981 – 1986

Senior Research Immunologist, Department of Immunology.

Responsible for the flowcytometry facility including production, testing, and evaluation of monoclonal antibodies for sexually transmitted diseases.

Stanford Medical Center, Stanford, California   1972 - 1981 Senior Research Assistant, Department of Genetics. 

Operator of early prototype flowcytometers and first B.D. FACS II.

Responsible for production of custom monoclonal antibodies for human therapy and conducted studies of murine lymphocytic antigens

Hewgill, Derek

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Imperial Cancer Research Fund, London, England  1971 –1972 

Senior Technician, Tumour Immunology Department, University College,

Coordinating start-up and maintenance of a new facility. Managing all Technical Staff.

Research in murine C-type particles.

Stanford Medical Center, Stanford, California.  1967 – 1971

Research Assistant, Department of Genetics

Conducted studies in immunology and genetics involving histocompatability Managed the mouse inbred production room. I was also involved in preparation of monospecific reagents by affinity chromatography and conjugation to fluorophores.

National Institute for Medical Research, London, England  1962 – 1967 

Junior Medical Technician, Department of Biological Standards 

Preparation, evaluation, and distribution of International Biological Standards, i.e. growth hormone, insulin, for worldwide distribution.

INSTRUMENT EXPERIENCE

Cytomation MoFLo High Speed Sorter.

Coulter Epics Elite ESP Medium Speed Sorter

Molecular Devices FLIPR (Fluorescence Imaging Plate Reader)

Bio-Rad MRC 1024 inverted and MicroRadiance compound

Confocal Imaging Microscopes

Becton Dickinson FACSorts

Becton Dickinson FACScans 

Ortho Cytofluorograf 

Coulter EPICS 753.  

Becton Dickinson FACSTAR .

Meridian ACAS 570

Coulter EPICS-C 

Becton Dickinson FACS IV

Becton Dickinson FACS II

 EDUCATION

Harrow Technical College, London, England.  1962 – 1965

 A Level Degree, Majors: Chemistry and Zoology.

Orange Hill Grammer School, London, England.  1956 – 1962

 O Level Degree.

Publications and References provided on request.